Why HOCl?

Pure&Clean could produce and market any number of antimicrobial solutions to reduce pathogens, but these always come with a cost to the delicate cells and critical growth factors required for patients to heal.  This only prolongs the healing process.

Pure&Clean has produced the most safe, effective, stable, trusted HOCl on the planet.  Through our patented processes and trade secrets, we are able to consistently deliver a product that healthcare professionals can trust. There’s nothing more powerful and effective than our HOCl solutions.  Others have tried to replicate Pure&Clean.  When we see other products in healthcare, we test their solutions for efficacy, safety and outcomes.  We also go head to head in case studies.  Each time we have compared Pure&Clean to other products, Pure&Clean has provided better patient outcomes.

What is HOCl?

When salt water is electrolyzed, it produces an anolyte solution that consists of >99.3% water, chloride salt and Hypochlorous Acid (HOCl). HOCl is a naturally occurring chemical that is produced by our neutrophils, a type of white blood cell, to fight bacteria and inflammation after an infection or trauma.

HOCl provides a unique power to eradicate dangerous organisms while not causing harm to our cells. HOCl is one of the only agents that is both non toxic to the delicate cells that can heal our wounds while being lethal to almost all known dangerous bacteria and viruses that threaten our health.

Why isn't Hypochlorous Acid everywhere?

The overwhelming impediment to its widespread use has been a lack of shelf stability. HOCl is the most reactive ROS (Reactive Oxygen Species). This means it reacts very easily and will quickly turn back into salt water.

HOCl solutions have been used for over 100 years. In the early 1900’s during World War I, HOCl solutions were used for dressing wounds and disinfecting medical equipment. However, until recently, HOCl solutions would only remain stable for about 90 minutes before turning back into salt water.

What has changed?

With Pure&Clean, HOCl is now manufactured in a way that allows the solution to be stable for much longer than previously possible. This has allowed Pure&Clean to produce and bottle HOCl so that it can be made available across the world. Although producing a cheap HOCl solution is not challenging, stabilizing a high-performing HOCl solution like Pure&Clean is very difficult and takes higher quality ingredients, equipment, and rigorous quality control measures. Pure&Clean produces pure HOCl that is electrochemically engineered in way that mimics the HOCl produced inside the human body.

At Pure&Clean, our quality ingredients and unique proprietary process produce an unmatched product. The process remains the only scalable manufacturing technology that can produce a pure and stable form of HOCl that contains no Hypochlorite (bleach), no alcohol, no ammonia, and has no other harmful contaminants, additives, or buffers. The result is a remarkably effective solution that promotes wound healing and effectively clears microorganisms from the wound bed.

This is proven by an industry-best 24-month shelf life on all Pure&Clean FDA-cleared products (not impacted by opening the bottle). Furthermore, we do not add unnecessary ingredients to stabilize or preserve our product stability. The Pure&Clean solution is so stable that we are able to offer a unique sprayable HOCl hydrogel blend – an innovation which proves to have a massive impact across a number of medical applications.

Mechanism of Action

Hypochlorous solution (HOCl) is a strong oxidizer. Its sodium hydroxide (NaClO) or its calcium hydroxide (Ca(ClO)2) are commonly used in deodorants and disinfectant products.

HOCl exists as a natural endogenous constituent in humans and animals and is an important part of the innate immune system. HOCl is produced by neutrophil granulocytes, the most abundant type of white blood cells in mammals. It is the last step of the Oxidative Burst Pathway in fighting infection and foreign substance invasion.

When a cell detects invasion of foreign substance it undergoes phagocytosis, during which the neutrophil ingests and internalizes microorganisms or foreign particles. HOCl exerts bactericidal properties and immediately destroys bacteria engulfed by the neutrophil.

Despite the substantial activity of HOCl against microorganisms, it is not cytotoxic to human or animal cells. This is probably related to its endogenous presence in the immune system of mammalian cells.